abstract |
The present invention provides an efficient method for producing a reagent capable of detecting an antibody having a specific bond to a poorly soluble antigen protein in a liquid sample, an antibody detecting reagent produced by the above production method, and a reagent thereof use. In the solubilization step of the antigen protein, the antigen protein can be efficiently dissolved by using the cationizing agent, and since it can be recovered, it can be efficiently produced as compared with the conventional method. An antibody detecting reagent that binds to a plurality of antigenic protein molecules. |