| abstract |
The present invention relates to epithelial sodium channel (ENaC) blocker 3-(3-{2-[(E)-3,5-diamino-6-chloro-pyrazine-2-carbonylimino]-1 , a novel crystalline form of succinic acid salt of 3,8-triaza-spiro[4.5]decane-8-carbonyl}-benzenesulfonylamino)-propionic acid dipropylamine-methylmethylmethyl ester, A pharmaceutical composition comprising the crystalline form, the crystalline form, and the use of the pharmaceutical compositions, and a method of preparing the crystalline form. |