http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201333208-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_f08f9f99db22bcca24642899da9fba65 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N11-14 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate | 2012-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6d080fd12cb64c772e9220adfd6550d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a8c5e4b7354da4a2e44f1eff28d02f7c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_476bfc1c1363ffc7f7ce502f14e8a50c http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_760f1851ea055a7a476284739ddb9018 |
publicationDate | 2013-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-201333208-A |
titleOfInvention | Biomolecular surface modification method |
abstract | The invention discloses a method for modifying the surface of a biomolecule. The upgrading method comprises the steps of: providing a biomolecule, the biomolecule binding at least one single strand of DNA, and the single strand of DNA binds to the first protein by affinity binding label; adding the second protein, and the concentration of the second protein Greater than the concentration of the first protein; and the first protein on the single strand of DNA is replaced by the second protein by chemical competition. Another modification method of the present invention comprises the steps of: providing a biomolecule, the biomolecule is combined with the first single-stranded DNA, the first single-stranded DNA has a first free energy between the biomolecule; and the second single-stranded DNA is added, The second single strand of DNA has a second free energy between the first strand of DNA and the second free energy is less than the first free energy; and the first single strand of DNA is detached from the biomolecule by thermodynamic principles and combined with the second single strand of DNA To restore the characteristics of the original biomolecule. |
priorityDate | 2012-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 183.