| abstract |
The present invention provides a binding polypeptide (eg, an antibody or a fragment thereof) that specifically binds to a target antigen (eg, a human antigen, such as human PDGFRβ) with high affinity. The invention also provides libraries, pharmaceutical compositions, and nucleic acids encoding the binding polypeptides, recombinant expression vectors, and host cells for use in the manufacture of such binding polypeptides. The invention also encompasses methods of using the binding polypeptides of the invention to diagnose and treat diseases. |