http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201332574-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_b61114c82148754b1906d9d4dcb043b2 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P17-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D303-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-19 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-336 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L59-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08G4-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-336 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-48 |
| filingDate | 2012-12-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90ec906bbb4f08e8e266024dd80fb2f3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5c9ad0a02317aa2133a4870b88453fe1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_de9b10613c8bc84668382362b5601408 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9922531a028db00549fe7c0e789ff0c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1c1218467a04f7246e35e8324b796c5e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_66fd78f71952a93603863008262c3414 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf0c758d4658830b1340d65bd3509e87 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_88bb2d218ef6cc5d0b795bed27851e6c |
| publicationDate | 2013-08-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201332574-A |
| titleOfInvention | Pharmaceutical formulation of fumagillin derivative-PHF conjugate |
| abstract | The invention as set forth herein provides a mixture comprising a polymer molecule or a salt thereof, wherein the polymer molecules in the mixture comprise covalently bonded subunits L, K and M, wherein the polymer molecules in the mixture The average molecular weight is from about 50 kDa to about 200 kDa, wherein the percentage of moles of the subunit M to the total number of subunits in the mixture is from about 90.5 to about 96 mole %, wherein the subunit K constitutes the subunit in the mixture. The molar percentage of the total amount is from about 2.8 to about 7.3 mole %, and wherein the percentage of moles of the subunit L to the total amount of the subunit in the mixture is from about 1.2 to about 2.2 mole %. The invention also provides a mixture comprising a polymer molecule or a salt thereof, wherein the polymer molecule in the mixture comprises a poly(1-hydroxymethyl-extended ethylhydroxymethyl-condensed covalently bonded with glutaric acid and compound D a formaldehyde) backbone wherein the average molecular weight of the polymer molecules in the mixture is from about 50 kDa to about 200 kDa, wherein the glutaric acid covalently bonded to the polymer molecular mixture comprises a total of subunits in the mixture The molar percentage of the amount is from about 2.8 to about 7.3 mol%, and wherein the percentage of moles of the compound D covalently bonded to the polymer molecular mixture to the total amount of the subunit in the mixture is from about 1.2 to about 2.2. Moer%. The invention also provides pharmaceutical formulations comprising a mixture of the invention. The invention also provides methods of making the mixtures of the invention and methods of using the mixtures and pharmaceutical formulations of the invention. |
| priorityDate | 2011-12-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 218.