| abstract |
The invention discloses a method for preparing 4,4-dialkoxy-1-buten-1-yl arene from crotonaldehyde and aryl diazonium salt, n-buten-1-altene and n-butane derived therefrom 1- aldehyde, its use as a fragrance, the use of this method for the preparation of anti-folate antifolates or folate anitmetabolites or Pemetrexed and for the preparation of antifolate An intermediate of antietoplastic antifolates or folate anitmetabolites or Pemetrexed. |