abstract |
Novel (2R,3S,5R)-2-(2,5-difluorophenyl)-5-[2-(methylsulfonyl)-2,6-dihydropyrrolo[3,4-c Pyrazol-5(4H)-yl]tetrahydro-2H-pyran-3-amine crystal form is a potent inhibitor of dipeptidyl peptidase-IV and is used to treat non-insulin dependent (type 2) diabetes . The invention also relates to pharmaceutical compositions containing such novel forms, methods of making the same, and pharmaceutical compositions thereof, and their use for the treatment of type 2 diabetes. |