| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_116c851e729089df9a427027272fa290 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-395
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-13
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K16-00 |
| filingDate |
2012-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_30e5b37c6bb2f0f80e67d06b3ce40c3e
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_95ce5fec044185c47c23e021851300cc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7878f997756d86a5e4dcddf011a3168
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6994f4e6a9cf28d7b2250317b58931aa |
| publicationDate |
2012-10-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201241182-A |
| titleOfInvention |
Method of production of sialylated antibodies |
| abstract |
The present invention relates to a method for producing an IgG antibody, wherein at least 80 % of the said antibody comprises a complex, bi-antennary oligosaccharide, which contains two sialic acid residues, attached to the Fc domain of the antibody. The said method comprises the steps of introducing a mutation in the Fc domain of the antibody, and expressing the mutant antibody in a cell which expresses a β galactosyltransferase and a sialyltransferase activity. |
| priorityDate |
2011-02-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |