http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201206950-A

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classificationCPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-301
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-30
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07F9-302
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B61-00
classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07F9-30
filingDate 2011-06-14-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_86545bec3969c02f307f1af43e4f0118
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a3c943a2b42ed2b1f2ec18cb7c7dbf9e
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publicationDate 2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-201206950-A
titleOfInvention Method for producing N-substituted-2-amino-4-(hydroxymethylphosphinyl)-2- butenoic acid
abstract Provided is an effective synthesizing method of a (Z)-N-substituted-2-amino-4-(hydroxymethylphosphinyl)-2-butenoic acid derivative. A compound expressed by a next chemical formula (1) (chemical formula 1) where R1 represents a hydrogen atom or a C1-4 alkyl group, and a compound expressed by a next chemical formula (2) (chemical formula 2) H2N-COR2 (2) where R2 represents a C1-4 alkyl group, C1-4 alkoxy group, aryl group, aryloxy group or benzyloxy group, are dehydro-condensed in the presence or absence of an acid catalyst to synthesize a (Z)-N-substituted-2-amino-4-(hydroxymethylphosphinyl)-2-butenoic acid derivative; in where an organic solvent used for the reaction is a mixed solvent of an acetic acid and a solvent selected from a group consisted of a toluene, xylene and chlorobenzene, where a mixing ratio of the acetic acid and the toher solvent is 1: 3 to 1: 5 in volume, and in which the reaction is conducted by heating under reflux.
priorityDate 2010-06-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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