| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a6e00aa18a20d67eed3ae0537ab22879 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2236-333
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2200-322
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23V2250-21 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A23L33-105
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K36-185
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 |
| classificationIPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P25-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K36-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A23L33-00 |
| filingDate |
2011-07-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cb484aacf84add5316df8ffd498967df
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f2c424d4af9c394513a9ef635a7873c6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d1b7f69708a6154176889b26aef1f3c1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1d3f59a206d28317840ba4df9504b34e |
| publicationDate |
2012-02-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201206454-A |
| titleOfInvention |
Pharmaceutical compositions for prevention or treatment of cerebrovascular disease, or for improving impairments, containing the extracts of Ilex latifolia as an active ingredient |
| abstract |
The present invention relates to compositions containing an active ingredient of Ilex latifolia extract for prevention or treatment of ischemic disease or degenerative brain disorders. Specifically, Ilex latifolia extract that is extracted with a solvent of water, alcohol or a mixture of water and alcohol is use shows suppression of brain infarction and edema in rats with induced cerebral infarction, and suppression of memory impairment in rats injected with amyloid β protein (A β (25-35)) to induce neurotoxicity, and confirms the ability of inhibiting oxidation reaction of hydrogen peroxide (H2O2)-induced, excitatory amino acids - glutamate, A β (25-35)-induced neurotoxicity, and hypoxia-induced cell death of cerebral cortical neurons. Therefore, the Ilex extract according to the present invention can be used as pharmaceutical compositions for the prevention or treatment of ischemic disease or degenerative brain disorders, or as the active ingredient of healthy foods. |
| priorityDate |
2010-08-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |