abstract |
The present invention relates to a method of enantioselective addition to imines, including: reacting R3CH=NY with R4ZnR5 in the presence of a compound represented by the following formual (I), in which Y, R1, R2, R3, R4 and R5 are defined the same as the specification. Accordingly, the present invention can prepare secondary amines in high yields and enantiomeric excess by the above-mentioned method. |