| abstract |
The present invention provides an application of 5-substituted 4,7-dimethoxy-1,3-benzodioxoles in manufacturing pharmaceutical products for treatment of colorectal cancer, wherein 5-substituted 4,7-dimethoxy-1,3 -benzodioxoles has the following general formula I: where R is selected from the following substituted or nonsubstituted groups: C1-C6 alkyl group, C2-C6 alkenyl group, C2-C6 alkynyl, cyano group, C1-C5 ester group, C1-C5 carboxylic group and isoxazole group, under the condition that R is non-methyl (other than -CH3). The invention also provides a pharmaceutical composition, cell cycle inhibitors, and colorectal cancer cytotoxic agents containing 5-substituted 4,7-dimethoxy-1,3-benzodioxoles. |