http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201124724-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e5be22daba9a408c368cc624ca089741 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5438 |
classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-547 |
filingDate | 2010-10-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_21091d6cc8922a37d3f1fffa8a925156 |
publicationDate | 2011-07-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-201124724-A |
titleOfInvention | Preparation method of antibody probe chip linking with electron-conducting anchoring molecule |
abstract | A method is disclosed for preparation of an antibody probe chip having electron-conducting anchoring molecules covalently bound to the metal film on the chip substrate. The antibody probe with covalent bonding electron-conducting anchoring molecules allow for fast and efficient molecular sample examination, characterization and measurement via binding to corresponding target molecule in a sample. Covalent bonding of the probes with the electron-conducting anchoring molecules on the chip substrate improves the stability and electronic conductivity of the molecular probe chip. Due to such stability improved, a test chip can be washed with adequate solution without substantial lost of molecules already bound to the probes. Due to such conductivity improved, the probes bound to the electron-conducting anchoring molecules can be applied in field of electro-sensing chips. Thorough cleaning of the chip reduces to minimum the interference from debris to the test, which leads to improved precision in the examination and characterization results. A antibody probe chip comprises a substrate having coated with a surface thereof a layer of metal film. First end of each of a number of electron-conducting anchoring molecules being directly bound to the metal film on the substrate, or being indirectly bound to the metal film with a linking compound, and an antibody probe is covalently bound to the second end of a corresponding one of the elongated anchoring molecules. |
priorityDate | 2009-01-06-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 69.