| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_7f6e33603375c486b0ab3505830af9e8 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C323-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-90
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C217-84
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C211-52
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C271-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D277-34 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D277-34
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-02 |
| filingDate |
2005-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2198beba502a5f0d1355299a322e6809
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3b96ba7eba67eff849cd05edcbff809f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1f3254c23b7593aecebfcfade1d11117
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_602bbbbd65a25d1d872d56c1af8f808d |
| publicationDate |
2011-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201121950-A |
| titleOfInvention |
The preparation method for 6-substituted-1-methyl-1H-benzoimidazol derivatives and their preparation imtermediates |
| abstract |
The present invention provides a preparation method for novel intermediate (IIa) and (III) for pharmaceutical active ingredient 6-substituted-1-methyl-1-H-benzimidazol derivative, and a method for scale up synthesis of intermediateN-(5)-substituted-2-nitrophenyl)-N-methyl amine (II). Furthmore, the present invention provides a method to efficiently prepare 6-substituted-1-methyl-1-H-benzimidazol derivatives (I) from preparation intermediate (II) via short process. The present invention is related to formula (I) compound, their preparation method and the preparation intermediate of compound (I) (wherein R2 is a phenyl group that can be substituted with C1-C6 alkyl group, X is oxygen, sulfur or nitrogen atom). |
| priorityDate |
2004-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |