http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201113277-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_cef4f341fe4f2caf061611a818576e40 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D285-135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-00 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-41 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D417-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-4523 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-433 |
| filingDate | 2010-09-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_31c795151433c6be206c5b07da051c62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8e89d6debc0db096f0ab30002b7362d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_41ea38f088c0de38ac7a86e648fc1581 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_185a1da18e83539fa5ad482b5ac73723 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7a7c3622d0ca497f1de8feda874e232f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d029c87c10536179a7e8b900742cfc1b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5eea21a2913797ce3b86ef0e4fb77f0 |
| publicationDate | 2011-04-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201113277-A |
| titleOfInvention | New thiadiazole derivatives |
| abstract | New thiadiazole derivatives having the chemical structure of formula (I) or a pharmaceutically acceptable salt or N-oxide or steroisomer thereof wherein wherein: L represents a direct bond or a -NH- group, R1 represents a phenyl, a pyridyl or a benzyl group which is optionally substituted with one or more substituents selected from halogen atoms, a C1-4 alkyl group, a C1-4 alkoxy group, a C3-7 cycloalkyl group and CN, -CONH2 and CF3 groups, R2 represents a C1-6 alkyl or a C1-4 alkyl-C3-7 cycloalkyl group, R3, R4 and R6 independently represent a hydrogen atom, a halogen atom, a C1-4 alkyl group or a CF3 group, R5 represents a -O-(CH2)(0-2)-Ra, -O-(CH2)(2-4)-NR'R'', -O-(CH2)(2-4)-NH-(CH2)(l-4)-R'', -(CH2)(l-2)-NR'R'', -(CH2)(l-4)-NH-(CH2)(l-4)-R'' or -(CO)-NR'R'', wherein Ra represents a 4 to 6-membered N-containing saturated heterocyclic group optionally substituted with one or more substituents selected from a hydroxycarbonyl group and C1-4 alkyl group substituted with hydroxycarbonyl group, or a C3-7 cycloalkyl group substituted with a di-(C1-4 alkyl)amino group which is itself optionally substituted with hydroxycarbonyl group, R' represents a hydrogen atom or a C1-4 alkyl group, R'' represents a methylsulfonamido group, a C2-4 alkanoyl group which is optionally substituted with a hydroxy group; a C1-4 alkyl group substituted with one or more substituents selected from a hydroxy group and a hydroxycarbonyl group; a 5- to 6-membered saturated or unsaturated heterocyclic group containing one or more heteroatoms selected from nitrogen and oxygen atoms and which is optionally substituted with hydroxy group; or a C4-6 cycloalkyl group substituted with a hydroxycarbonyl group, or R' and R'' together with the nitrogen atom to which they are attached form a 4 to 6 membered, saturated or unsaturated heterocyclic group which contains, as heteroatoms, the N atom to which R' and R'' are attached and 0, 1 or 2 further N atoms, which heterocyclic group is optionally substituted with one or more substituents selected from a cyano, a carbamoyl, hydroxycarbonyl, C1-3 alkoxycarbonyl and 1H-tetrazolyl groups and C1-3 alkyl group which is optionally substituted by a hydroxycarbonyl group. |
| priorityDate | 2009-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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