abstract |
Disclosed is a novel pyridazinone compound having an activity of inhibiting P2X7 receptor that is a kind of purine receptor, which is useful in preventing, treating or ameliorating diseases relating to inflammation or immunity. Specifically disclosed is a novel pyridazinone compound represented by formula (I) [wherein R1, R2, Q, X, Y and Z are each as defined in the description], a tautomer of said compound, a prodrug thereof, a pharmaceutically acceptable salt thereof or a solvate of the same. |