http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-201039869-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a8886a895aa420f149ae0bc75212c2bc |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61M1-18 |
| filingDate | 2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_43518a74d44b7be089edb99a77c01f08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff356928d2fcd98d837b7a03e438d305 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5500f7c9d80a9561cb5158d7a9d6d2a3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a805be6bcd52b51ead68264c4ef6c82 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_17d868a264d322d2c06abf12203666dc |
| publicationDate | 2010-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-201039869-A |
| titleOfInvention | Modified polysulfone hemodialyzer and method of manufacturing the same |
| abstract | In order to develop a hemodialyzer with functions of anti-oxidation and absorption of endotoxins, the present invention provides a hemodialyzer, which immobilizes sialic acid onto the surface of a polysulfone (PSF) hollow fibrous film. The present invention uses ozone to treat PSF hollow fibrous film in order to produce per-oxy radicals on the surface of film. Furthermore, the per-oxy radicals develop a free radical polymerization reaction with acrylic acid monomers. Subsequently, ethyl-dimethyl carbodiimide hydrochloride (EDC) is used to activate carboxyl groups on the surface. Finally, sialic acid molecules are immobilized on the surface of hollow fibrous film. The modified hollow fibrous film immobilized with sialic acid has conspicuously increased power in absorbing lipopolysaccharide (LPS) and removal of reactive oxygen, and does not conspicuously affect the configuration of material and hemocompatability thereof. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113230898-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-113230898-A |
| priorityDate | 2009-05-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 96.