| abstract |
The invention relates to the novel products of formula (I): in which R4 represents H, CH3, CH2CH3, CF3, F, Cl, Br or I; Het represents a heterocycle optionally substituted with one or more R1 or R'1 radicals chosen from H, halogen, CF3, nitro, cyano, alkyl, hydroxyl, mercapto, amino, alkylamino, dialkylamino, alkoxy, phenylalkoxy, alkylthio, carboxyl in free form or esterified with an alkyl radical, carboxamide, CO-NH(alkyl), CON(alkyl)2, NH-CO-alkyl, sulphonamide, NH-SO2-alkyl, S(O)2-NHalkyl and S(O2)-N(alkyl)2, all these alkyl, alkoxy and alkylthio radicals being themselves optionally substituted; R is chosen from the group constituted of: W1, W2 and W3 independently represent CH or N; X represents O, S, NR2, C(O), S(O) or S(O)2; V represents H, Hal, -O-R2 or -NH-R2 with R2 representing H, alkyl, cycloalkyl or heterocycloalkyl, which are optionally substituted; these products being in all the isomeric forms and the salts, as medicaments. |