| abstract |
The invention relates to the novel products of formula (I): in which represents a single or double bond; Rb represents a hydrogen atom or a fluorine atom; Ra represents an -NH-Rc radical in which Rc represents an optionally substituted heterocycloalkyl, aryl, heteroaryl or alkylcycloalkyl radical; X represents S, SO or SO2; A represents NH or S; W represents H; alkyl or COR with R representing cycloalkyl; alkyl; alkoxy; O-phenyl; -O-(CH2)n-phenyl with n= 1 to 4; or NR1R2 with R1 representing H or alk and R2 representing H, cycloalkyl or alkyl; or else R1, R2 form, with N, a ring optionally containing O, S, N and/or NH; all these radicals being optionally substituted; these products being in any of the isomer forms and the salts, as medicaments, especially as MET inhibitors. |