| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_75b765b53e6651e9863a3a35e4c1e164 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-41
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2317-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K17-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K16-18 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-537 |
| filingDate |
2009-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_eda3df4a02e1a529345ab36087727aa3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_da05692ba8b51b072bf798aefa44ddb3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9e12fae1a9fab3ad14ac9f7c97064ded
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_90bfa82e88835bccf1897dd569ff9997
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e622b23a4553033eba2795349bdaa97 |
| publicationDate |
2010-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-201028692-A |
| titleOfInvention |
Method for immobilizing protein |
| abstract |
A method for immobilizing protein includes steps of providing a surface; contacting a boronic acid to the surface, wherein the boronic acid is represented as Y-R-B-(OH)2 and includes a boric acid group(B-(OH)2), a linker R, and a functional group Y, in which the boronic acid is bonded to the surface via the functional group Y; and contacting a protein containing a Fc (Fragment, crystallizable) region to the boronic acid, wherein two spatially adjacent hydroxyl groups of a sugar chain of the Fc region form a boronate ester with the boric acid group of the boronic acid to immobilize the protein. The goal of site-specific and covalent protein immobilization without interfering the binding affinity of an antibody to epitopes is thus achieved with the reaction of boronic acid and Fc region according to the present invention. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I788986-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I754939-B |
| priorityDate |
2009-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |