abstract |
A compound having the structure wherein X is selected from the group consisting of: a bond, -NHCH2(CH2)nCH2OC(O)-, -CH2NHC(O)CH2NHC(O)-, -CH2OC(O)-, -OCH(CH3)OC(O)-, -OCH2OC(O)-, -O-, -NR1-, -CR1R3-, -(CH2) p-, -(CH2) qNR1C(O)-, -CHR5NR2C(O)-, -(CH2)qC(O)-, -(CH2)qC(O)NR1-, or a pharmaceutically acceptable salt thereof, and methods of using the compounds for treating hypertension. |