| abstract |
The present invention is related to the compounds related with galactosylceramide which is represented by Formula (1) or (2). (wherein X, Y is S or O, R1, R2 is a alkyl group or alkenyl group with carbon number of 9-35, and R3 is a alkyl group or alkenyl group with carbon number of 2-30.) The present invention provides a β -glucocerebrosidase activator which is easily available for the improvement of the formation of keratin transmission barrier by the activation of β -glucocerebrosidase and expected effect on the improvement of rough skin in result; a skin external preparation; and a method for the activation of β -glucocerebrosidase. |