| abstract |
The subject of the present invention is compounds corresponding to formula (I): in which: X represents a bivalent(C1-C5)alkylene radical that is unsubstituted or substituted; R1 represents: a group -NR8R9; a piperidin-3-yl or piperidin-4-yl radical that is unsubstituted or substituted; R2 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group; R3 represents a hydrogen atom, a halogen atom, an Alk group, an OAlk group; R4 represents a hydrogen atom, a halogen atom, an Alk group, a hydroxyl, an OAlk group; R5 represents a hydrogen atom, a halogen atom, an Alk group, a hydroxyl, an OAlk group; R6 represents a hydrogen atom, a halogen atom, an Alk group, a hydroxyl, an OAlk group; R7 represents a hydrogen atom, a halogen atom, an Alk group, a hydroxyl, an OAlk group; R8 and R9 each independently represent a hydrogen atom or a (C1-C4)alkyl; or alternatively R8 and R9, together with the nitrogen atom to which they are attached, constitute a heterocyclic radical; Alk represents a (C1-C4)alkyl that is unsubstituted or substituted once or several times with a fluorine atom, in the form of a base or of an addition salt with an acid. Method of preparation and therapeutic application. |