| abstract |
The present invention aims to provide a novel pyrazole derivative and a pharmaceutical agent containing the same. The present invention provides a compound represented by the formula (I') wherein R1' is (1) a hydrogen atom, (2) a group via a carbon atom, (3) a group via a nitrogen atom, (4) a group via an oxygen atom or (5) a group via a sulfur atom; R2' is an aromatic ring group optionally having substituent(s); R3' is (1) a hydrogen atom, (2) a group via a carbon atom, (3) a group via a nitrogen atom, (4) a group via an oxygen atom or (5) a group via a sulfur atom; R4' is a cyanophenyl group optionally having substituent(s); X' is (1) - Y'-CR5'R6'-Z' - wherein R5' and R6' are the same or different and each is a hydrogen atom, a group via a carbon atom, a group via a nitrogen atom, a group via an oxygen atom or a group via a sulfur atom, or -CR5'R6'-is -C(alkylidene)-; Y' is a bond, -COCO-, -CONH-, -COCONH- or -0-; and Z' is a bond, -CH2-, -CONH-, -O-, -OCH2-, -S-, -SO-, -SO2-, -CON(C6H5)- or (2) -CO(CONH)n- wherein n is 0 or 1, (3) -NHCO-, (4) -CONH-, (5) -O-, (6) -CH=CH- or (7) -O(C1-3 alkylene)O-; (excluding the compounds indicated to be excluded from the specification), or a salt thereof. |