| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_aa241ea658c6f62d997856f8d6534df1 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-107
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-05
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-215 |
| filingDate |
2007-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81db78332f540e65bd02f6b591c6f30b
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_073677aebfbfccf7fe249afcef0976bc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a35b26c28e8c9aaa3c672365608507b2
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_484f5b4793e3373083217a8fa62429bd
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f6dea0ccec701139a1d2d88456044435
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e742f90926baaf41f43467eb30b0283d |
| publicationDate |
2009-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-200914063-A |
| titleOfInvention |
The formulation of skin permeable polyphenols-encapsulated nanoemulsion |
| abstract |
This invention is to claim the composition and the method for preparing a polyphenols-encapsulated nanoemulsion. This claimed formula includes polyphenols dissolved in vegetable oils, phospholipids and a surfactant, of which the HLB value is larger than 1. This preparation is conducted in an ultrasonic water bath with frequency of 2 kHz-50 MHz for suitable time. The particle size of this claimed polyphenols-encapsulated nanoemulsion droplet ranges from 5 to 100 nm, which facilitates skin permeation. This formulation is stable in diluted PBS up to 1000-fold for over 6 month. In addition to enhance the skin permeation rate, this formula uses biocompatible surfactant with low toxicity and may provide a resolution for the low bioavailability of polyphenols. The equipments and process in this claimed method is simple. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I643639-B
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112956691-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112641096-A
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-112641096-B |
| priorityDate |
2007-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |