| abstract |
The present invention relates to an extract of Myrothecium sp. mycelium used to inhibit growth of tumor cell, particularly relating to compounds of verrucarin A and verrucarin J segregated from the Myrothecium sp. Mycelium which can effectively inhibit growth of cells of the hepatoma, lung cancer, and prostate cancer. In the present invention, the compounds of verrucarin A and verrucarin J can be applied in inhibiting growths of Hep3B and HepG2 of the human hepatoma cells, A549 of the human lung cancer cell, and LNCaP and DU-145 of the human prostate cancer cells, and simultaneously can be used in the medicament composition of inhibiting growth of cells of the hepatoma, lung cancer, and prostate cancer. |