| abstract |
The present invention provides compounds of the following formula, the pharmaceutically acceptable salt thereof, or the solvate thereof: (wherein, cycle A represents, cycle B represents a heteroaryl group which may be substituted(except for substituted isoxazolyl group) or heterocycle group which may be substituted, R1 represents hydrogen atom or alkyl group which may be substituted, R2 represents-OR5, -SR5, halogen atom or haloalkyl group, etc. , R3 represents alkyl group which may be substituted, etc., R4 represents alkyl group which may be substituted, etc., R5 represent alkyl group which may be substituted, etc., R6 represents hydrogen atom, etc., R7 and R8 each represents hydrogen atom, etc., R10 and R11 each represents hydrogen atom, etc, R12 represent alkyl group which may be substituted, etc., m and p each represents integer of 1 to 3), which can be used as inhibitor of 11 β -hydroxysteroid dehydrogenase type I. |