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classificationIPCInventive http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-552
filingDate 2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c88ed07bf134b6c4c014110698daf5b3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c920090dcd2bd99fe04c913d960df371
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publicationDate 2008-12-16-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-200848737-A
titleOfInvention Modified SiO2 particles with DNA-binding ability and methods for producing and using thereof
abstract The present invention provides a method for synthesizing SiO2 nanoparticles with controllable surfaces. The method includes mixing SiO2 powder with a coupling agent having a silane functional group in an organic solution for improving its quality. The surface electric potential of the SiO2 nanoparticles with improved surface quality manufactured by the present invention can be changed by the amino group. The SiO2 nanoparticles hence produced can be linked to DNA by the ionic bond stably, and then this linked complex can be separated by the pH in different solution. Through the present invention, the nanoparticles are able to be used as purifier or concentrator of DNA, which provide an increased industry utility.
priorityDate 2007-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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