| abstract |
Disclosed is a novel compound having a strong FXa inhibitory activity and exhibits quick, sufficient and lasting antithrombotic effect even by oral administration. Specifically disclosed is a compound represented by the general formula (I) below, a pharmacologically acceptable salt thereof or an FXa inhibitor containing any of them as an active ingredient. (In the formula, ring A represents a benzene ring; R1 represents a hydrogen atom, a halogeno group or the like; R2 represents a carboxy group, a carbamoyl group or the like; T1 represents a -NHC=O- group or the like; T2 represents a -CH2-C(=O)NH- group or the like; Q1 represents a tetrahydronaphthy- ridinyl group, a tetrahydrothiazolopyridyl group or the like; Q2 represents a single bond,1-4-phenylene and etc.; and Q3 represents a phenyl group, a pyridyl group or the like.) |