| abstract |
The present invention relates to novel enfumafungin derivatives of formula IV-1A and pharmaceutically acceptable salts thereof, their synthesis, and their use as inhibitors of (1,3)-beta-D-glucan synthase. The present compounds and pharmaceutically acceptable salts thereof, as well as pharmaceutical compositions comprising the present compounds and pharmaceutically acceptable salts thereof, are useful for treating or preventing antifungal infections and associated diseases and conditions. |