abstract |
It is intended to provide an agent having at least one of actions of improving a vascular endothelial function and suppressing vascular intimal thickening with excellent safety, which can improve a function related to the vascular endothelium, has an action of preventing various diseases related to a vascular endothelial function or suppressing vascular intimal thickening, and can be expected to have an effect on preventing arteriosclerosis or the like. The agent of the invention comprises, as an active ingredient, (a) Xaa Pro Pro, or (b) a hydrolysate of animal milk casein containing Xaa Pro Pro or a concentrate thereof, or (c) a fermented substance containing Ile Pro Pro and/or Val Pro Pro obtained by fermenting a raw material containing milk protein with a bacterial strain belonging to the Lactobacillus helveticus species. |