http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-200804426-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_404ad3939c28be90e799904b88ef1f06 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K19-00 |
| filingDate | 2006-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_641e6c0a5a8a117905259c2c28b3e8d8 |
| publicationDate | 2008-01-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-200804426-A |
| titleOfInvention | Fusion protein of porcine reproductive and respiratory syndrome virus as PRRS vaccine |
| abstract | The present invention provides a fusion protein, PE-PQAB-K3, of Porcine Reproductive and Respiratory Syndrome Virus (PRRSV) for use as a vaccine for porcine reproductive and respiratory syndrome (PRRS), which comprises Pseudomonas exotoxin domain I (combination domain-transposition domain II), a PQAB structural peptide which comprises the N-terminals of ORF5 and ORF 6 of PRRSV and binds the cell receptors, and a signal code, KDEL-KDEL-KDEL (KDEL3), linking at the carboxyl terminal of the fusion protein. The serum samples obtained from the mice or pigs immunized with the PE-PQAB-K3 fusion protein of the present invention can inhibit the growth and reproduction of PRRSV in MAC-10A cells, and the neutralization titer can reach the range from 16 to 32. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I473813-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I385249-B http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-9657063-B2 |
| priorityDate | 2006-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 114.