| abstract |
This invention relates to stabilized aerosol solution formulations containing acid addition salts of salbutamol, which are suitable for administration by metered dose inhalers (MDIs). More particularly, this invention relates to solution formulations containing one of the aforementioned salts of salbutamol, preferably salbutamol hydrochloride or salbutamol citrate, more preferably one of the two before mentioned salts in combination with one or more additional pharmacologically active substances, together with an environmentally safe hydrofluorocarbon (HFC) as a propellant, a co-solvent, preferably an organic compound as a co-solvent, and either an inorganic acid or an organic acid. |