http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-200732308-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_0a9e6421e9257148abad101e1ce6c162 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P43-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P13-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-24 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D405-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P3-04 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D401-12 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-94 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-517 |
| filingDate | 2006-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_58788bc22a57c07ce0f946c9dab99c10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ae376f8e5d192cd3a1d3d723ff26bd05 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cf1607674d41964bbb319094fa44068b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54e62c06ae29d5593027bff747761a99 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12eda797b56da0e16e7feb2169383c1f |
| publicationDate | 2007-09-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-200732308-A |
| titleOfInvention | Substituted 4-aminoquinazoline derivatives, preparation thereof and therapeutic application thereof |
| abstract | The invention relates to 4-aminoquinazoline derivatives of general formula (I), in which: A, B = optionally substituted C1-4-alkylene; L = single bond, C1-2-alkylene, -CH=CH- or -C≡C-; the groups C1-2-alkylene and -CH=CH- being optionally substituted, or L = cyctoprop-1,2-diyl;R = H, C1-5-alkyl, C1-3-fluoroalkyl, C3-6-cydoalkyl, - C(O)C1-3-alkyl, C1-3-alkylene-C3-6-cycloalkyl, -CH2-C≡CH, C2-4-alkylene-NRaRb or C1-3-alkylene-X-C1-3-alkyl in which X = O, SO2; R1 = aryl or heteroaryl; optionally substituted; R2 and R3 = H, C1-3-alkyl or C1-3-fluoroalkyl, or alternatively R2 and R3 together form a cycloprop-1,1-diyl; R4 = H, C1-5-alkyl, C1-3-fluoroalkyl, C1-5-alkoxy, -SF5, C1-3-alkylene-X-C1-3-alkyl in which X = O or SO2, C1-5-alkylene-NRaRb, an aryl or a heteroaryl, which are optionally substituted; R5 = H, halogen, C1-5-alkyl, C1-3-fluoroalkyl, C1-5-alkoxy, C3-6-cycloalkyl, C1-3-alkylene-C3-6-cycloalkyl, C1-3-alkylene-O-C1-3-alkyl, C1-3-alkylene-(OH) or C1-3-alkylene-X-C1-3-alkyl in which X = S, SO or SO2, or alternatively R5 = -NRaRb, C1-3-alkylene-NRaRb, aryl, C1-3-alkylene-aryl, -O-aryl, C1-3-alkylene-O-aryl, C1-3-alkylene-O-C1-3-alkylene-aryl, heteroaryl or C1-3-alkylene-heteroaryl, which are optionally substituted, or R5 = heterocycle optionally substituted with C1-3-alkyl, -C(O)C1-3-alkyl, -C(O)C1-3-fluoroalkyl, C1-3-alkylene-C3-6-cycloalkyl, C1-3-alkylene-aryl, C1-3-alkylene-heteroaryl, which are optionally substituted; R7 = H, halogen, C1-5-alkyl, C1-3-fluoroalkyl, C1-5-alkoxy, -COOH, -C(O)O-C1-3-alkyl, C1-3-fluoroalkoxy, C1-3-alkylene-(OH), -NO2, -CN or -X-C1-3-alkyl in which X represents S, SO or SO2, or alternatively R7 = -NRaRb, C1-3-alkylene-NRaRb, -C(O)-NRaRb, -C(o)-C1-3-alkyl, aryl, -O-aryl or heteroaryl, which are optionally substituted; in the form of base or of acid-addition salt, and also in the form of hydrate or solvate. |
| priorityDate | 2005-10-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 32.