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filingDate 2005-06-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_70cf9588c0370fe2d86dbda1cd962d8b
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publicationDate 2006-06-01-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber TW-200616967-A
titleOfInvention Novel indazole carboxamides and their use
abstract The invention is directed to novel indazole derivatives. Specifically, the invention is directed to compounds according to Formula I: , wherein R1 and Z are defined below, and to pharmaceutically-acceptable salts thereof. The compounds of the invention are inhibitors of IKK2 and can be useful in the treatment of disorders associated with inappropriate IKK2 (also known as IKKβ) activity, such as rheumatoid arthritis, asthma, and COPD (chronic obstructive pulmonary disease). Accordingly, the invention is further directed to pharmaceutical compositions comprising a compound of the invention. The invention is still further directed to methods of inhibiting IKK2 activity and treatment of disorders associated therewith using a compound of the invention or a pharmaceutical composition comprising a compound of the invention.
isCitedBy http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-I380973-B
priorityDate 2004-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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Total number of triples: 43.