| abstract |
A naphthalene derivative represented by the following general formula (I) or a pharmacologically acceptable salt of the derivative. They have human SGLT inhibitory activity and are useful as a preventive or therapeutic agent for diseases attributable to hyperglycemia, such as diabetes and obesity. In the chemical structural formula, R1 to R6 each is hydrogen, OH, NH2, etc.; R7 and R8 each is hydrogen, OH, halogen, etc.; Q is alkyline, alkylene, etc.; ring A is aryl, heteroaryl, etc.; and G is a group represented by the following general formula (G-1) or (G-2); E1 is hydrogen, fluorine or OH; E2 is hydrogen, fluorine or methyl group. |