abstract |
Compounds of the formula (I): where R2, R5, R6 have the meanings as given in the description, and U, V and W, respectively, may be CR2', CR4' and CR6', respectively (with the definitions of R2', R4' and CR6' again as in the description), or may be N, were synthesized. They were found down-regulate or inhibit the expression or function of the IGF-1 receptor. |