http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-200530155-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_42e94091a4fc81b8d0237117707cc7ee |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C2603-74 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C327-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C231-02 |
| classificationIPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C233-48 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C327-22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C231-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C323-22 |
| filingDate | 2005-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12664253b9ca1b8fd38706605c460f0e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_743549ef0381adb01ab22d4e2f5c8ff4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51ed526dd0252ad94fabb04545f337d7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_81b4e2d081092cece87c2dd3155888a5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d58e9696302abcdba7f3a50378252fa4 |
| publicationDate | 2005-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-200530155-A |
| titleOfInvention | Novel alkyl- and aryl-thiotrifluoroacetates and process |
| abstract | Novel C3-C19 alkyl- and aryl-thiotrifluoroacetates are provided which have the structure, wherein Q is C9-C19 alkyl or aryl, and are useful protecting agents for the amino or hydroxy functional groups of amines, amino acids or primary or secondary alcohols or amino alcohols to enable formation of amide bonds in peptides or proteins which are useful as screening agents, pharmaceuticals and cosmetics. A process for preparing C3-C19 alkyl- and aryl-thiotrifluoroacetates is also provided wherein a C3-C19 alkylthiol or arylthiol is treated with trifluoroacetic anhydride (TFAA) in the presence of organic base such as pyridine, a solvent such as dichlororoethane (DCM) and dimethylaminopyridine (DMAP) as a catalyst to form the desired C3-C19 alkyl- or aryl-thiotrifluoroacetate. In addition, a process for protecting a primary or secondary amino group or a primary or secondary hydroxyl group or an amino alcohol with a trifluoroacetyl protecting group is provided wherein a primary or secondary amine, amino acid, a primary or secondary alcohol or an amino alcohol is treated with a C3 to C19 alkyl- or aryl-thiotrifluoroacetate in basic aqueous solution. |
| priorityDate | 2004-01-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 136.