| abstract |
The present invention relates to the novel derivatives of formula (I) in which, A is, if it is present, a (C1-C6) alkyl radical, a (C3-C6) alkenyl radical, a (C3-C6) alkynyl radical, a (C3-C7) cycloalkyl radical or a (C5-C7) cycloalkenyl radical, R1 is an NR6R7, (C4-C7) azacycloalkyl, (C5-C7) azacycloalkenyl, (C5-C9) azabicycloalkyl or (C5-C9) azabicycloalkenyl group; A-R1 is such that the nitrogen of R1 and the nitrogen in the 1-position of the pyrazole are necessarily separated by at least two carbon atoms, R3 is an H, halogen, OH, SH, NH2, Orc, SRc, SORa, SO2Ra, NHCHO, NRaRb, NHC(O)Ra, NHC(S)Ra or NHSO2Ra radical, R4 is an aryl or heteroaryl radical; and R5 is an H, halogen, CF3, CHF2, CH2F, linear or branched (C1-C6) alkyl or (C3-C7) cycloalkyl radical, to their racemates, enantiomers and diastereoisomers and to their mixtures, their tautomers and to their pharmaceutically acceptable salts. |