| abstract |
The present invention is related to a compound represented by the general formula (I), salts thereof, solvates thereof, prodrugs thereof or cyclodextrin inclusion compound of the same, (wherein all the symbols are as defined in the description). Because the compounds of the present invention have strong agonistic action to EP2, strong effect of reducing intraocular pressure and small irritation to eyes, they are useful in treating eye diseases such as glaucoma, ocular hypertension, macular edema, macular degeneration, the decrease in blood flow of retina and optic papilla, the rise in tension of retina and optic nerve, myopia, hyperopia, astigmatism, xerophthalmia, retinal detachment, cataract and so on. |