| abstract |
This invention provides 19-nor-D-homosteroids, having a mixed androgenic/progestagenic profile, which are orally active, prevent trabecular bone mineral density (BMD) loss, and which lack liver toxicity, having a structure according to the formula 1: formula wherein, R1 is O, or NOR, with R being hydrogen, (C1-6) alkyl or (C1-6) acyl, R2 is methyl or ethyl, and R3 is hydrogen or (C1-15) acyl. |