http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-200518757-A
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4cdb1ef9fe36ae01e3729156a7103103 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02P20-55 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P3-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D239-42 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D239-42 |
| filingDate | 2004-12-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_388613527e8021db292a3df2eef7661f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9932c3ae5bb42e467755650164bb01d5 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1f4b6f1d7148c55380336fc87e117b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5ddb192179775fe7cdb5d3bc3e6078e8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_852d1d6e3c06444a4a45ca074047ef2b |
| publicationDate | 2005-06-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | TW-200518757-A |
| titleOfInvention | Process for the preparation of pyrimidine derivatives |
| abstract | An improved process for the preparation of pyrimidine derivatives is provided comprising reacting a Wittig reagent of the general formula, wherein R is an alkyi of from 1 to 10 carbon atoms, aryl or arylalkyl, R1 is a substituted or unsubstituted hydrocarbon group, R2 and R3 are the same or different and are hydrogen or a substituted or unsubstituted hydrocarbon group; Z is sulfur, oxygen, sulfonyl, or imino which may be substituted by formyl, acetyl, propionyl, butyryl, isobutyryl, valeryl, isovaleryl, amino substituted by sulfonyl or alkylsulfonyl, and sulfonyl substituted by alkyi, amino or alkylamino and X is a halogen; with an aldehyde of the general formula, wherein R4 is hydrogen, a lower alkyl or a cation capable of forming a non-toxic pharmaceutically acceptable salt and each R5 are the same or different and are hydrogen or a hydrolyzable protecting group, or each R5 together with the oxygen atom to which each is bonded, form a hydrolyzable cyclic protecting group, or each R5 is bonded to the same substituent which is bonded to each oxygen atom to form a hydrolyzable protecting group; in the presence of a base. |
| priorityDate | 2003-12-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 33.