| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_c76ecadad74a1a35270b3e3a34d60f37 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-75
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D213-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P29-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P31-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-73
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D213-75 |
| filingDate |
2003-11-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6670a503864c9bcaec96b6b6ed073658
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06610f6cb903496fe14f3a406de274a8 |
| publicationDate |
2004-12-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
TW-200426140-A |
| titleOfInvention |
Substituted pyridines via boronic acid coupling |
| abstract |
The invention relates to a convergent process for preparing a compound of the formula (V), wherein R1 is attached at the 2 or 3 position of the benzene ring, R2 is attached at the 5 or 6 position and R1, R2 and G are as defined herein, in which an aryl boronic acid is coupled with an amine protected halo-substituted-2-aminopyridine using a palladium coupling agent. Compounds of formula V are useful as nitric oxide synthase (NOS) inhibitors in a mammal. |
| priorityDate |
2002-11-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |