http://rdf.ncbi.nlm.nih.gov/pubchem/patent/TW-200423946-A
Outgoing Links
Predicate | Object |
---|---|
assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_40765ca9a78b54a8a76f781d159ad145 |
classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-675 |
filingDate | 2004-01-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dc42f1929a0c745c0ba325b51ec26331 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e0312276d7b0be43aafc6f01a186f9a7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_727f9e840c7d1eb70e2da7ef9a722259 |
publicationDate | 2004-11-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber | TW-200423946-A |
titleOfInvention | Compositions and methods for combination antiviral therapy |
abstract | The present invention relates to therapeutic combinations of [2-(6-amino-purin-9-yl)-1-methyl-ethoxymethyl]-phosphonic acid diisopropoxycarbonyloxymethyl ester (tenofovir disoproxil fumarate, Viread) and (2R, 5S, cis)-4-amino-5-fluoro-1-(2-hydroxymethyl-1,3-oxathiolan-5-yl)-(1H)-pyrimidin-2-one (emtricitabine, EmtrivaTM, (-)-cis FTC) and their physiologically functional derivatives. The combinations may be useful in the treatment of HIV infections, including infections with HIV mutants bearing resistance to nucleoside and/or non-nucleoside inhibitors. The present invention is also concerned with pharmaceutical compositions and formulations of said combinations of tenofovir disoproxil fumarate and emtricitabine, and their physiologically functional derivatives, as well as therapeutic methods of use of those compositions and formulations. |
priorityDate | 2003-01-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 396.