| abstract |
The present invention provides a compound represented by the general formula (I), (wherein, all the symbols are as same as those described in the specification), quartery ammonium salts, N-oxides and salts thereof. The compound represented by the general formula (I) is useful as the prophylactic and/or the treatment for various inflammations (asthma, nephritis, nephropathy, hepatitis, arthritis, chronic articular rheumatism, rhinits, conjunctivitis, ulcerative colitis and the like), immune disease (autoimmune diseases, immune suppression, psoriasis, multiple sclerosis and the like), human immune deficiency virus infection (acquired immune deficiency syndrome and the like), allergy diseases (atopic dermatitis, hives, allergic bronchopulmonary aspergillosis, allergic acidophilic gastrointestinal diseases and the like), ischemic reperfusion injury, sever acute respiratory syndrome, shock associated with bacteria infection, diabetes, cancer metasis and the like. |