| abstract |
The present invention provides a pharmaceutical preparation that can improve absorption of a pharmaceutical compound in the gastrointestinal tract and that provides, through oral administration or like method, a blood concentration from which sufficient remedial effects can be expected, and a method for production such a preparation. The invention is directed to a pharmaceutical preparation exhibiting excellent gastrointestinal absorbability comprising a compound recognized by a proton-coupled transporter and a Ph-sensitive polymer in an amount sufficient for the gastrointestinal tract to acquire a Ph at which the proton-coupled transporter optimally absorbs the compound into a cell. |