| abstract |
The invention relates to the use of cyclooxygenase-2 inhibitors or derivatives thereof in preventing and treating preterm labor. In particular, the invention describes the pharmaceutical composition for preventing and treating preterm labor in a subject, said pharmaceutical composition comprising a therapeutically-effective amount of a compound of formula I or II, wherein R1, R2, R3 R4, R5 and R6 are as described in the specification provided that the compound in not 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl] benzenesulfonamide (celecoxib). |