| abstract |
The present invention relates to a aminoalcohol derivative or a phosphonic acid derivative of the formula (I) [wherein, R1 and R2: H or an amino-protecting group; R3: H or a hydroxy-protecting group; R4: a lower alkyl group; n: an integer of 1-6; X: oxygen atom or nitrogen atom unsubstituted or substituted with a lower alkylene group etc.; Y: ethylene group; Z: a C1-10 alkylene group; R5: an aryl group or a substituted aryl group; R6 and R7: H, provided that when R5 is H, then Z is a single bond or a group other than a straight C1-10 alkylene group; ], or the pharmaceutically acceptable esters or the pharmaceutically acceptable salts thereof, which have the excellent immusuppressive effects, and the pharmaceutical composition containing thereof. |