| abstract |
Compounds having the formula (I), wherein R3 is selected from H, OH and NH2; R30 is selected from = O and = S; W is -C (=O)-, -S (=O)-, or -S (O) 2-; or W may be -CH2- if X is -C (=O)-; X is selected from - CH2-, -N (R4)-, and -O-, except that when W is -CH2-, X is - C (=O)-; Y is a bond or -C (R40) (R45)-; Q is a linker; Z is optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, aryl, heteroaryl, or heterocyclyl; and R1, R2, R24, and R25 are as defined in the specification. |