| abstract |
The present invention relates to a 4-oxoqinoline derivative of the formula (I) [wherein, R1: aryl group etc.; R2: a lower alkyl group etc.; R3: a group of the formula -A-D-E-Gn+(X-)n (wherein, A: oxygen atom etc.; D: a C1-12 alkylene group etc.; E: a single bond etc.); Gn+ : a substituted anmonio group etc.; X-: anion; n: an integer of 1 or 2; R4, R6 and R7: H etc.; R5: H etc.; ring Ar: aryl group etc.], or the pharmaceutically acceptable salts or esters, or the other derevatives thereof having an excellent ileum-type bile acid transporter inhibitory effect. |